Naphcon -A eye drops This medication is used to temporarily relieve eye redness? puffiness? itching? and watering that commonly occur with allergies. Naphazoline is a decongestant. It belongs to a class of drugs known as sympathomimetic amines. It works by temporarily narrowing the blood vessels in the eye. Pheniramine is an antihistamine. It works by blocking certain natural substances (histamines) that cause allergic symptoms.Do not use this medication to treat redness and irritation from wearing contact lenses.